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Gluten intolerance or coeliac disease? Understanding the difference

Date:
13/08/2025
Author:
Ellie Jones

Do you ever feel a general discomfort after eating bread, pasta, or other gluten-containing foods? You're not alone. Many people experience digestive upset, fatigue, or other puzzling symptoms after consuming gluten. This often leads to a big question: is it a simple sensitivity, or something more serious like coeliac disease?

The distinction between gluten intolerance and coeliac disease is crucial, not just for how you feel day-to-day, but for your long-term health. While both involve reactions to gluten, the underlying mechanisms and implications for your body are quite different.

This blog post will clarify what gluten intolerance and coeliac disease are, highlight their key differences, explore common symptoms, and explain why understanding this distinction truly matters for your well-being. We'll also look at how accessible at-home testing can provide a valuable first step in gaining insights into your body's response to gluten, helping you make informed decisions about your diet and your health journey.

What is gluten intolerance (non-coeliac gluten sensitivity)?

Gluten intolerance, or non-coeliac gluten sensitivity (NCGS), describes a situation where a person experiences adverse symptoms after eating gluten, but they do not have coeliac disease or a wheat allergy. It’s thought to be more common than coeliac disease, though pinpointing exact numbers is tricky.

The precise mechanisms behind gluten intolerance are still being explored. It doesn't involve the same autoimmune response as coeliac disease. Instead, it's considered more of a sensitivity or difficulty in processing gluten or perhaps other components often found alongside gluten in grains.

Gluten intolerance symptoms

The symptoms of an intolerance can be varied and aren't always limited to the digestive system. Common signs include:

- Bloating

- Gas and flatulence

- Abdominal pain or cramping

- Diarrhea or constipation (or alternating)

- Nausea

These signs often appear hours or even a day or two after consuming gluten and typically improve when gluten is removed from the diet. While uncomfortable and disruptive to daily life, NCGS does not cause the same kind of permanent damage to the body as coeliac disease.

Understanding coeliac disease

On the other hand, coeliac disease is a more serious, autoimmune condition triggered by consuming gluten. Unlike gluten intolerance, coeliac disease is not a sensitivity but a condition where the body's immune system mistakenly attacks its tissues when gluten is present.

Specifically, the immune system attacks the lining of the small intestine. This causes damage to the villi, tiny, finger-like projections that absorb nutrients from food. When the villi are damaged, the body struggles to absorb essential vitamins and minerals.

This malabsorption can lead to a range of health problems beyond just digestive upset.

Coeliac disease symptoms

Unlike gluten intolerance, the signs of coeliac disease aren't always straightforward.

What makes coeliac disease particularly challenging to identify is its wide range of symptoms; some individuals experience very few, or even no, noticeable digestive issues at all.


Beyond the well-known digestive discomforts, the symptoms of coeliac disease can manifest throughout the entire body. As an autoimmune condition that directly damages the small intestine when gluten is consumed, impairing your body's ability to absorb vital nutrients.

This malabsorption can lead to a diverse array of effects that extend far beyond initial gut feelings.


Common coeliac disease symptoms include:


- Persistent digestive upset (diarrhoea, bloating, pain)
- Ongoing fatigue and low energy
- Unexplained weight loss
- Iron-deficiency anaemia
- Itchy skin rash
- Bone or joint pain
- Brain fog or concentration issues
- Recurrent mouth ulcers


Because coeliac disease involves ongoing autoimmune damage to the small intestine, it carries potential risks for long-term health considerations if left unmanaged. Understanding these broader implications underscores why recognising and addressing this condition is so important for your well-being.

Gluten intolerance vs coeliac disease: the key differences

So, what are the crucial points when comparing gluten intolerance vs coeliac disease?

The most significant difference lies in the body's reaction to gluten. Coeliac disease is an autoimmune response that causes damage to the small intestine. Gluten intolerance is a sensitivity that causes symptoms but does not lead to intestinal damage or long-term autoimmune complications.

Think of it like this: someone with a mild lactose intolerance might get a stomach ache after drinking milk, but it won't cause permanent harm. Someone with a severe dairy allergy could have a life-threatening reaction involving their immune system. While not a perfect analogy, it highlights the difference in the type of reaction and its potential severity.

Another key difference is the diagnostic process. Coeliac disease can be identified through specific blood tests that look for certain antibodies, followed by a biopsy of the small intestine (usually done via endoscopy) to confirm the villi damage. These tests need to be performed while the person is still eating gluten, as removing gluten can cause the markers to disappear, making diagnosis difficult.

For gluten intolerance, there isn't a specific test to confirm it. It's often identified by ruling out coeliac disease and wheat allergy, and then seeing if symptoms improve on a gluten-free diet. This makes understanding the distinction even more important.

Why understanding the distinction matters

Knowing the difference between gluten intolerance and coeliac disease is vital for several reasons:

Health management: Coeliac disease requires a strict, lifelong gluten-free diet to prevent ongoing intestinal damage and long-term health problems. Even small amounts of gluten can cause harm. For gluten intolerance, the level of gluten that triggers symptoms can vary from person to person, and some may tolerate small amounts.

Nutritional needs: Coeliac disease can lead to nutrient deficiencies due to malabsorption. Simply removing gluten might not be enough; addressing these deficiencies is key. While gluten-free diets can also be low in certain nutrients (like fibre and B vitamins), malabsorption isn't the primary issue with NCGS.

Testing: Specific tests exist for coeliac disease (like antibody blood tests), but not for gluten intolerance. If you suspect a reaction to gluten, testing for coeliac disease is usually the first step to rule out this more serious condition.

This is where gaining insights through accessible testing can be incredibly useful.

Taking the first step: considering a Coeliac test

If you've been experiencing persistent symptoms after eating gluten, you're not alone. Many people wonder if gluten is the root cause. Getting clearer information is the first step towards managing how you feel and making informed decisions about your diet and lifestyle.

A gluten intolerance test can be a valuable starting point. It offers a way to check for markers related to coeliac disease from the privacy and convenience of your own home.

The benefits of an at-home test

Using a Gluten Intolerance (Coeliac Disease) Home Rapid Test provides a straightforward way to check for the presence of IgA and IgG antibodies commonly found in people with coeliac disease. These are the antibodies your immune system produces in response to gluten if you have the condition.

These tests use just a small blood sample, often from a simple finger prick. They are designed to be user-friendly, with clear instructions that guide you through the process step-by-step. Getting a result at home offers a discreet way to get insights without the need to immediately visit a clinic.

It's important to remember that while these rapid tests can indicate the presence of relevant antibodies, they are not a substitute for a full clinical assessment. If a home test suggests the presence of these antibodies, it's an indicator that further discussion with a healthcare professional is recommended.

Clarity for confident choices

Experiencing symptoms after eating gluten can be frustrating, impacting everything from your energy levels to your social life. Taking a proactive approach to understanding why you feel the way you do is key.

Utilising accessible at-home tools can be a simple way to get valuable preliminary insights. It cuts through some of the guesswork and provides clear data that can serve as a springboard for further conversations with healthcare professionals if needed.

Remember, gaining clarity on whether your symptoms might be linked to coeliac disease or perhaps gluten intolerance is the first step towards finding effective ways to manage your health and improve your well-being.

Accessible, reliable, and user-friendly home tests are designed to make that crucial initial step simpler, empowering you to live more confidently and comfortably


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